Development of a two-dimensional LC–MS/MS system for the determination of proline and 4-hydroxyproline enantiomers in biological and food samples
Chiharu Ishii, Yosuke Tojo, Komei Iwasaki, Akira Fujii, Takeyuki Akita, Masanobu Nagano, Masashi Mita, Tomomi Ide, Kenji Hamase
Topics & Concepts
ChemistryHydroxyprolineChromatographyEnantiomerProlineTandem mass spectrometryAmino acidLiquid chromatography–mass spectrometryMass spectrometryStereochemistryBiochemistryAmino Acid Enzymes and MetabolismMetabolism and Genetic DisordersDiet and metabolism studies