TNFR2 deficiency impairs the growth of mouse colon cancer
Ping Li, Yang Yang, Xinyu Yang, Yifei Wang, Chon‐Kit Chou, Mengmeng Jiang, Jingbin Zheng, Fengyang Chen, Xin Chen
Abstract
TNFR2 plays a role in the growth of mouse colon cancers. Our study provides further experimental evidence to support the development of TNFR2 antagonistic agents in the treatment of cancer.
Topics & Concepts
Cancer researchCancerColorectal cancerIn vivoOvarian cancerCD8Tumor necrosis factor alphaCytotoxic T cellCancer cellIn vitroImmunologyBiologyMedicineImmune systemInternal medicineBiotechnologyBiochemistryImmune Cell Function and Interactioninterferon and immune responsesImmunotherapy and Immune Responses