Litcius/Paper detail

Commercially available rapid diagnostic tests for the detection of high priority pathogens: status and challenges

Jaime Castillo, Ramona Trebbien, John J. Castillo, Winnie Edith Svendsen

2021The Analyst29 citationsDOIOpen Access PDF

Abstract

The ongoing COVID-19 pandemic has shown the importance of having analytical devices that allow a simple, fast, and robust detection of pathogens which cause epidemics and pandemics. The information these devices can collect is crucial for health authorities to make effective decisions to contain the disease's advance. The World Health Organization published a list of primary pathogens that have raised concern as potential causes of future pandemics. Unfortunately, there are no rapid diagnostic tests commercially available and approved by the regulatory bodies to detect most of the pathogens listed by the WHO. This report describes these pathogens, the available detection methods, and highlights areas where more attention is needed to produce rapid diagnostic tests for future pandemic surveillance.

Topics & Concepts

Turnaround timeOutbreakDiagnostic testPublic healthLimited resourcesDisease surveillanceMedicineBusinessRisk analysis (engineering)Environmental healthMedical emergencyOperations managementEngineeringVirologyPathologyEmergency medicineViral Infections and Outbreaks ResearchMosquito-borne diseases and controlSARS-CoV-2 detection and testing