RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection
Patrick W. Cervantes, Bruno Martorelli Di Genova, Billy Joel Erazo Flores, Laura J. Knoll
Abstract
Toxoplasma gondii infection activates pattern recognition receptor (PRR) pathways that drive innate inflammatory responses to control infection. Necroptosis is a proinflammatory cell death pathway apart from the innate immune response that has evolved to control pathogenic infection.
Topics & Concepts
NecroptosisBiologyProinflammatory cytokineToxoplasma gondiiProgrammed cell deathInnate immune systemImmunologyImmune systemInflammationAntibodyApoptosisBiochemistryToxoplasma gondii Research StudiesCell death mechanisms and regulationInflammasome and immune disorders