Metal-free catalytic nucleophilic substitution of primary alcohols with secondary phosphine oxides
Xiantao Ma, Xiaoyu Yan, Jing Yu, Jiarui Guo, Jiakun Bian, Ran Yan, Qing Xu, Li‐Biao Han
Abstract
The first dehydrative version of the Michaelis–Arbuzov reaction was developed, and two possible dehydration pathways were proposed.
Topics & Concepts
PhosphinePrimary (astronomy)CatalysisChemistryNucleophilic substitutionOrganic chemistryMetalNucleophileSubstitution (logic)Substitution reactionAstronomyProgramming languageComputer sciencePhysicsAsymmetric Hydrogenation and CatalysisChemical Synthesis and ReactionsOrganophosphorus compounds synthesis