Micelle-Derived Palladium Nanoparticles for Suzuki–Miyaura Coupling Reactions in Water at Room Temperature
Siyuan Wu, Shihui Zhang, Xinxin Yang, Xuemin Liu, Xin Ge
Abstract
Despite the wide utility of colloidal palladium (Pd) nanoparticle (NP)-catalyzed Suzuki–Miyaura cross-coupling reactions in laboratory and industrial synthesis, the easy construction of colloidal Pd NPs and the detailed role of surfactants remain the focus of attention. Here, we present a simple and sustainable strategy to construct a nanoreactor by connecting micelles with Pd NPs. The strategy enables us to employ a pH-induced morphological transition of sugar-based surfactant aggregates, such as worm-like, spherical, and tubular micelles, to investigate the solubilization of organic substrates. Pd NPs are mainly synthesized by the reduction of phenylboronic acid, further stabilized by the sugar-based surfactant micelles. A kinetic model is established, and the apparent activation energy of this reaction in aqueous micellar solutions is determined to be 46.7 kJ/mol. Notably, the recycled aqueous reaction mixture containing the micelles and Pd NPs can be reused.