On the selective killing of cold atmospheric plasma cancer treatment: Status and beyond
Dayun Yan, Alex Horkowitz, Qihui Wang, Michael Keidar
Abstract
Abstract Compared with many chemotherapy and radiotherapy modalities, selective killing of cancer cells is a pivotal feature of cold atmospheric plasma (CAP). Understanding its underlying mechanism will build the foundation of CAP‐based cancer treatment. Additionally, we provided forward‐looking thinking to extend the definition of selectivity from conventional cases involving a single‐cell line to a coculture case. Finally, the newly established physically based treatment strategy provides unprecedented visions to realize selectivity beyond the previously established concepts based on reactive species and direct killing effect.
Topics & Concepts
Atmospheric-pressure plasmaSelectivityModalitiesVisionCancer treatmentCancerFoundation (evidence)ChemistryCancer researchPlasmaNanotechnologyMaterials scienceMedicinePhysicsInternal medicinePolitical scienceBiochemistrySociologyAnthropologySocial scienceCatalysisLawQuantum mechanicsPlasma Applications and DiagnosticsPlasma Diagnostics and ApplicationsNanoplatforms for cancer theranostics