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Clinical characteristics of COVID-19 patients with HIV coinfection in Wuhan, China

Rongrong Yang, Xien Gui, Yongxi Zhang, Yong Xiong, Shicheng Gao, Hengning Ke

2020Expert Review of Respiratory Medicine27 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Information about the impact of HIV coinfection on clinical characteristics of COVID-19 patients remains limited. METHODS: Maximum body temperatures, fever duration, chest CT and viral shedding, lymphocyte counts, and titer of SARS-CoV-2 antibody were compared between COVID-19 patients with and without HIV infection in Zhongnan Hospital of Wuhan University from January 20th to February 14th, 2020. RESULTS: = 0.813). CONCLUSION: T lymphocyte counts caused by HIV infection itself might be one of reasons for relatively weak ability to produce SARS-CoV-2 specific antibodies. The effects of anti-HIV drugs in prevention and treatment of COVID-19 appears to be limited.

Topics & Concepts

CoinfectionMedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Internal medicineTiterHuman immunodeficiency virus (HIV)AntibodyViral sheddingGastroenterologyImmunologyDiseaseInfectious disease (medical specialty)COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19
Clinical characteristics of COVID-19 patients with HIV coinfection in Wuhan, China | Litcius