Metal‐free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl<sub>3</sub> to Alkenes
Nikolaos F. Nikitas, Errika Voutyritsa, Petros L. Gkizis, Christoforos G. Kokotos
Abstract
Abstract A simple, photochemical, and metal‐free protocol for the atom transfer radical addition (ATRA) of bromotrichloromethane onto various alkenes is described. Among a range of organic molecules, phenylglyoxylic acid proved to be the most suitable photoinitiator to promote a sustainable process for the addition of bromotrichloromethane to olefins. This photochemical atom transfer radical protocol can be expanded into a wide substrate scope of aliphatic olefins bearing various functional groups, leading to the corresponding products in good to excellent yields.
Topics & Concepts
ChemistryPhotochemistrySubstrate (aquarium)PhotoinitiatorAtom (system on chip)Hydrogen atomMetalRadicalOrganic chemistryGroup (periodic table)OceanographyComputer scienceGeologyPolymerEmbedded systemMonomerRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods