Wnt/β-catenin signaling in colorectal cancer: Is therapeutic targeting even possible?
Cyrollah Disoma, Yuzheng Zhou, Shanni Li, Jian Peng, Zanxian Xia
Topics & Concepts
Wnt signaling pathwayAdenomatous polyposis coliCancer researchCarcinogenesisColorectal cancerSignal transductionBiologyCateninLGR5Mouse model of colorectal and intestinal cancerTranscription factorEpithelial–mesenchymal transitionCancer stem cellCancerCell biologyGeneticsGeneMetastasisWnt/β-catenin signaling in development and cancerCancer-related gene regulationDigestive system and related health