C–H Electrophilic (phenylsulfonyl)difluoromethylation of (hetero)arenes with a newly designed reagent
Enzo Nobile, Thomas Castanheiro, Tatiana Besset
Abstract
A new electrophilic (phenylsulfonyl)difluoromethylating reagent was easily prepared and offered a versatile tool for the synthesis of PhSO 2 CF 2 S-containing molecules.
Topics & Concepts
ReagentElectrophileChemistrySurface modificationCombinatorial chemistryMoleculeChemical spaceTransition metalOrganic chemistryDrug discoveryCatalysisPhysical chemistryBiochemistryFluorine in Organic ChemistryInorganic Fluorides and Related Compounds