Electrochemical Strategy for Low-Cost Viral Detection
Marjon Zamani, James Robson, Andy Fan, Michael S. Bono, Ariel L. Furst, Catherine M. Klapperich
Abstract
total copies of input nucleic acids, which is a clinically relevant viral load for HPV DNA. Further, proof-of-concept experiments with cervical swab samples, extracted using standard extraction protocols, demonstrated that the strategy is extendable to complex human samples. This adaptable technology could be applied to detect any viral infection rapidly and cost-effectively.
Topics & Concepts
Viral loadLoop-mediated isothermal amplificationHuman immunodeficiency virus (HIV)PopulationVirologyCervical cancerHuman papillomavirusMedicinePoint-of-care testingComputational biologyImmunologyCancerBiologyDNAInternal medicineGeneticsEnvironmental healthCRISPR and Genetic EngineeringHIV Research and TreatmentBacteriophages and microbial interactions