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Xylazine-associated Wounds: Clinical Experience From a Low-barrier Wound Care Clinic in Philadelphia

Rachel McFadden, Sara Wallace-Keeshen, Kristi Petrillo Straub, Rebecca A. Hosey, Rachel Neuschatz, Keara McNulty, Ashish P. Thakrar

2023Journal of Addiction Medicine59 citationsDOIOpen Access PDF

Abstract

ABSTRACT: The veterinary sedative xylazine is spreading in unregulated opioid supplies across North America. Among people who use drugs with repeated exposure to xylazine, a distinct wound type has emerged. Here, we describe these wounds and share our experience treating them in a nurse-led, low-barrier wound care clinic in Philadelphia, PA. We propose a reimagining of wound treatment across settings to better serve people who use drugs, and we advocate for stronger protections against the harms of an increasingly adulterated drug supply. Our perspective from the epicenter of the xylazine crisis can inform the response of communities across the country who are starting to face harms associated with xylazine.

Topics & Concepts

MedicineXylazineWound careIntensive care medicineEmergency medicineAnesthesiaFamily medicineKetamineVeterinary Pharmacology and AnesthesiaForensic Toxicology and Drug AnalysisForensic Entomology and Diptera Studies
Xylazine-associated Wounds: Clinical Experience From a Low-barrier Wound Care Clinic in Philadelphia | Litcius