Recent Advances in Diagnostic Approaches for Mucormycosis
Jawad Safiia, M. Díaz, Hassan Alshaker, Christine Atallah, Paul Sakr, Dimitrios G Moshovitis, Ahmad Nawlo, Andres E Franceschi, Alexis Liakos, Sophia Koo
Abstract
Mucormycosis, an invasive fungal infection caused by members of the order Mucorales, often progresses fulminantly if not recognized in a timely manner. This comprehensive review discusses the latest developments in diagnostic approaches for mucormycosis, from traditional histopathology and culture-based methods to advanced and emerging techniques such as molecular assays, imaging, serology, and metabolomics. We discuss challenges in the diagnosis of mucormycosis and emphasize the importance of rapid and accurate identification of this life-threatening infection.
Topics & Concepts
MucormycosisMucoralesBiologyIdentification (biology)Intensive care medicineMedicinePathologyEcologyAntifungal resistance and susceptibilityFungal Infections and StudiesOral microbiology and periodontitis research