Significance of Competitive Reactions in an Atmospheric Pressure Chemical Ionization Ion Source: Effect of Solvent
Younes Valadbeigi, Tim Causon
Abstract
as an alternative reactant ion (RI) to ionize the analytes via electrophilic substitution. Density functional theory (DFT) was used to study the different paths of ionization. The theoretical and experimental results showed that by using only the absolute thermodynamic data, the real ionization path cannot be determined and the energies of all competing processes such as charge transfer, protonation, and hydride abstraction need to be compared.
Topics & Concepts
ChemistryAtmospheric-pressure chemical ionizationChemical ionizationIonizationHydrideIon sourceMass spectrometryProtonationIonAnalytical Chemistry (journal)Organic chemistryHydrogenChromatographyMass Spectrometry Techniques and ApplicationsAnalytical Chemistry and ChromatographyAdvanced Chemical Sensor Technologies