T-cell engaging poly(lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing cancer
Ramesh Duwa, Ram Hari Pokhrel, Asmita Banstola, Mahesh Pandit, Prakash Shrestha, Jee‐Heon Jeong, Jae‐Hoon Chang, Simmyung Yook
Topics & Concepts
Cytotoxic T cellPLGACD8CytotoxicityMaterials scienceCancer cellIL-2 receptorT cellCancer researchImmune systemInternalizationAntigen-presenting cellAntigenCell biologyChemistryMolecular biologyCellIn vitroBiologyCancerImmunologyNanotechnologyBiochemistryNanoparticleGeneticsCAR-T cell therapy researchImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers