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A brief review on the palladium-catalyzed C–H activation reactions of 2-phenylpyridines

Jesly Joy, T. D. Demina, Amruta Kush Durgi, Ajesh Vijayan

2025RSC Advances10 citationsDOIOpen Access PDF

Abstract

position of 2-phenyl pyridine has been identified as a prime target for C-H activation due to its unique electronic and steric properties. This mild and selective transformation has enormous applications in the chemical field, such as drug discovery, natural products, agrochemical, and pharmaceutical industries. These highly regioselective, chemo-selective, eco-friendly reactions exhibit a wide substrate scope. This review accounts for the development of various palladium-catalyzed C-H functionalisation reactions of 2-phenyl pyridine.

Topics & Concepts

PalladiumRegioselectivityCatalysisScope (computer science)ChemistryPyridineCombinatorial chemistryOrganic chemistryComputer scienceProgramming languageCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsNanomaterials for catalytic reactions
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