3D printed membranes of polylactic acid and graphene oxide for guided bone regeneration
Hee Jeong Jang, Moon Sung Kang, Won‐Hyeon Kim, Hyo Jung Jo, Sung-Ho Lee, Eun Jeong Hahm, Jung Hyun Oh, Suck Won Hong, Bongju Kim, Dong‐Wook Han
Abstract
We fabricated graphene oxide (GO)-incorporated polylactic acid (PLA) (GO-PLA) films by using three-dimensional (3D) printing to explore their potential benefits as barrier membranes for guided bone regeneration (GBR). Our results showed that the 3D printed GO-PLA films provided highly favorable matrices for preosteoblasts and accelerated new bone formation in rat calvarial bone defect models.
Topics & Concepts
Polylactic acidRegeneration (biology)GrapheneMembraneMaterials scienceOxide3d printedNanotechnologyComposite materialBiomedical engineeringChemistryEngineeringCell biologyBiochemistryBiologyMetallurgyPolymerGraphene and Nanomaterials ApplicationsBone Tissue Engineering Materials3D Printing in Biomedical Research