Sotorasib: a KRASG12C inhibitor for non-small cell lung cancer
Arghya Ganguly, Euna Yoo
Topics & Concepts
KRASChemistryStereochemistryCysteineLung cancerCovalent bondRing (chemistry)PyridineCancer researchMedicinal chemistryInternal medicineBiochemistryMedicineMutationOrganic chemistryEnzymeGeneProtein Kinase Regulation and GTPase SignalingProtein Tyrosine PhosphatasesMelanoma and MAPK Pathways