Gasdermin D-dependent platelet pyroptosis exacerbates NET formation and inflammation in severe sepsis
Meiling Su, Chaofei Chen, Shaoying Li, Musheng Li, Zhi Zeng, Yuan Zhang, Luoxing Xia, Xiuzhen Li, Dezhong Zheng, Qiqi Lin, Xuejiao Fan, Ying Wen, Yingying Liu, Feiyan Chen, Wei Luo, Yun Bu, Jinhong Qin, Manli Guo, Miaoyun Qiu, Lei Sun, Renjing Liu, Ping Wang, John Hwa, Wai Ho Tang
Topics & Concepts
PyroptosisSepsisInflammationNeutrophil extracellular trapsPlateletTLR4MedicineImmunologyDownregulation and upregulationProinflammatory cytokineInflammasomeChemistryGeneBiochemistryInflammasome and immune disordersNeutrophil, Myeloperoxidase and Oxidative MechanismsImmune Response and Inflammation