Soluble ST2 in Ambulatory Patients With Heart Failure: Association With Functional Capacity and Long-Term Outcomes
Tariq Ahmad, Faı̈ez Zannad, Dalane W. Kitzman, Mona Fiuzat, Ileana L. Pin a, Kirkwood F. Adams, Linda K. Shaw, Vivian P. Thompson, David J. Whellan, G. Michael Felker, Megan L. Neely, Mark Donahue, William E. Kraus, Christopher M. O Connor
Abstract
ST2 is involved in cardioprotective signaling in the myocardium and has been identified as a potentially promising biomarker in HF. We evaluated ST2 levels and their association with functional capacity and long-term clinical outcomes in a cohort of ambulatory heart failure (HF) patients enrolled in the HF-ACTION study—a multicenter, randomized study of exercise training in HF.
Topics & Concepts
AmbulatoryTerm (time)Association (psychology)MedicineHeart failureInternal medicineCardiologyPsychologyPsychotherapistPhysicsQuantum mechanicsIL-33, ST2, and ILC Pathways