Controllable <i>Z</i>/<i>E</i>-selective synthesis of α-amino-ketoximes from <i>N</i>-nitrososulfonamides and aryl alkenes under neutral conditions
Pan‐Feng Yuan, Tao Huang, Jian He, Xie‐Tian Huang, Xiaoling Jin, Chun‐Lin Sun, Li‐Zhu Wu, Qiang Liu
Abstract
An amidoximation of alkenes with N -nitrososulfonamides enabled by triplet energy transfer under neutral conditions is presented. Both ( Z )- and ( E )-α-amino-ketoximes are selectively accessible depending on the triplet energy of the photosensitizer.
Topics & Concepts
ChemistryArylPhotosensitizerEnergy transferPhotochemistryMedicinal chemistryCombinatorial chemistryOrganic chemistryChemical physicsAlkylSynthesis and Catalytic ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods