Microglia in Central Control of Metabolism
Jung Dae Kim, Francesca Copperi, Sabrina Diano
Abstract
Beyond their role as brain immune cells, microglia act as metabolic sensors in response to changes in nutrient availability, thus playing a role in energy homeostasis. This review highlights the evidence and challenges of studying the role of microglia in metabolism regulation.
Topics & Concepts
MicrogliaEnergy metabolismImmune systemNeuroscienceHomeostasisMetabolismMetabolic regulationBiologyNutrient sensingEnergy homeostasisCentral nervous systemCell biologyInflammationImmunologySignal transductionBiochemistryEndocrinologyReceptorNeuroinflammation and Neurodegeneration MechanismsAtherosclerosis and Cardiovascular DiseasesImmune cells in cancer