Litcius/Paper detail

A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

Philippos Demetriou, Enas Abu‐Shah, Salvatore Valvo, Sarah McCuaig, Viveka Mayya, Audun Kvalvaag, Thomas Starkey, Kseniya Korobchevskaya, Lennard Y. W. Lee, Matthias Friedrich, Elizabeth H. Mann, Mikhail A. Kutuzov, Matteo Morotti, Nina Wietek, Heather Rada, Shamsideen Yusuf, Jehan Afrose, Anastasios Siokis, Oxford IBD Cohort Investigators, Philip Allan, Timothy Ambrose, C Arancibia, Adam Bailey, Ellie Barnes, Elizabeth Bird‐Lieberman, Jan Bornschein, Oliver Brain, Barbara Braden, Jane Collier, Jeremy Cobbold, Emma Culver, James East, Lucy Howarth, Paul Klenerman, Simon J. Leedham, Rebecca Palmer, Michael Pavlides, Fiona Powrie, Astor Rodrigues, Jack Satsangi, Alison Simmons, Peter M. Sullivan, Holm H. Uhlig, Alissa Walsh, Michael Meyer‐Hermann, Ahmed A. Ahmed, David Depoil, Michael L. Dustin

2020Nature Immunology136 citationsDOIOpen Access PDF

Topics & Concepts

Immunological synapseCell biologyCD28Cytotoxic T cellT-cell receptorT cellBiologyCD8CD3KinaseSignal transductionImmunologyAntigenImmune systemGeneticsIn vitroImmune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers