The discovery of a new potent FXR agonist based on natural product screening
Zongwen Yao, Lin Chen, Min Hu, Fancheng Meng, Min Chen, Guowei Wang, Guowei Wang
Topics & Concepts
ChemistryFarnesoid X receptorNatural productBile acidBiochemistrySmall heterodimer partnerBilirubinCholesterol 7 alpha-hydroxylaseDocking (animal)Transcription factorPharmacologyNuclear receptorGeneEndocrinologyBiologyNursingMedicineDrug Transport and Resistance MechanismsCancer therapeutics and mechanismsDrug-Induced Hepatotoxicity and Protection