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Let-7a inhibits Bcl-xl and YAP1 expression to induce apoptosis of trophoblast cells in early-onset severe preeclampsia

Wenhui Zha, Shuang Guan, Ning Liu, Yang Li, Yuan Tian, Yang Chen, Yan Wang, Fuju Wu

2020The Science of The Total Environment23 citationsDOI

Topics & Concepts

YAP1ApoptosisDNA methylationCell growthBiologyBcl-xLMethylationDownregulation and upregulationTrophoblastMolecular biologyCell biologyViability assayCancer researchProgrammed cell deathGene expressionGeneTranscription factorGeneticsPlacentaFetusPregnancyPregnancy and preeclampsia studiesMicroRNA in disease regulationBirth, Development, and Health
Let-7a inhibits Bcl-xl and YAP1 expression to induce apoptosis of trophoblast cells in early-onset severe preeclampsia | Litcius