Coronary Plaque Quantification with Ultrahigh-Spatial-Resolution Photon-counting Detector CT: Intraindividual Comparison with Energy-integrating Detector CT
Milán Vecsey-Nagy, Giuseppe Tremamunno, U. Joseph Schoepf, Chiara Gnasso, Emese Zsarnóczay, Nicola Fink, Dmitrij Kravchenko, Moritz C. Halfmann, Jim O’Doherty, Bálint Szilveszter, Pál Maurovich‐Horvat, Ismail Kabakus, Pál Surányi, Tilman Emrich, Ákos Varga‐Szemes
Abstract
= .13). Total, calcified, and fibrotic plaque volumes demonstrated excellent agreement between repeated measurements and between readers for both PCD CT and EID CT (all intraclass correlation coefficients [ICCs] > 0.90). Whereas low-attenuation plaque volume had strong intrareader (ICC, 0.84; 95% CI: 0.57, 0.94) and interreader (ICC, 0.92; 95% CI: 0.81, 0.97) agreements for PCD CT, EID CT showed only moderate (ICC, 0.62; 95% CI: 0.11, 0.86) and poor (ICC, 0.47; 95% CI: 0.01, 0.79) intrareader and interreader reproducibility. Conclusion Compared with EID CT, PCD CT UHR imaging reduced segmented coronary plaque volume by nearly one-third and improved reproducibility of low-attenuation plaque measurements. © RSNA, 2025