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Investigation of calcium silicate as a natural clay‐based sunblock: Formulation and characterization

Naseem Abbas, Suryyia Manzoor, Saira Saeed, Syed M. Husnain, Muhammad Tariq, Zeeshan Akhtar, Naveeda Saira, Ghazala Yasmin

2020Photodermatology Photoimmunology & Photomedicine10 citationsDOI

Abstract

Abstract Background Sunlight exposure causes several types of health issues to humans, and in particular, it affects especially the skin. Among the most common harmful issues developed by UV exposure are erythema, pigmentation, and lesions in DNA, which may lead to cancer. These long‐term effects can be minimized with the use of sunscreen. Objective The use of commercial UV filters causes severe side effects such as skin allergy and whitening of the skin. Therefore, in this study the effectiveness of Ca 2 SiO 4 , a compound abundantly present in the soils of certain South Asian regions, has been the first time explored as UV filter. This compound leaves a low amount of white residue on the skin and is highly stable. Method The comparative study of a cosmetic formulation having 5% Ca 2 SiO 4 , and other formulations containing 5% TiO 2 and 5% ZnO as inorganic UV filters, was performed to evaluate the physical and chemical stability. Result The zeta potential and chemical stability of formulations containing these different UV filters were investigated by using UV‐Vis spectroscopy, FTIR‐ATR, and X‐ray diffraction. Results indicated Ca 2 SiO 4 as a promising innovative UV filter with an SPF value of 37.94. One of the reasons is its low interaction with organic filter, that is, PABA, as compared to commercial ZnO and TiO 2 inorganic UV filters. Biological absorption in organs was studied by ICP‐MS on model mice. Conclusion It also has a low photocatalytic activity; thus, formation of radicals is minimum. Moreover, Ca 2 SiO 4 showed a recognized ability to leave a low amount of white residue on the skin combined with great stability.

Topics & Concepts

UV filterZeta potentialErythemaPhotocatalysisMaterials scienceFourier transform infrared spectroscopyChemistryNuclear chemistryChemical engineeringDermatologyNanotechnologyOrganic chemistryMedicineCatalysisPhysicsEngineeringOpticsNanoparticleTherapeutic Uses of Natural ElementsSkin Protection and AgingClay minerals and soil interactions
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