Regulation of the cerebrovascular smooth muscle cell phenotype by mitochondrial oxidative injury and endoplasmic reticulum stress in simulated microgravity rats via the PERK-eIF2α-ATF4-CHOP pathway
Ran Zhang, Min Jiang, Jibin Zhang, Ya Qiu, Danyang Li, Sulei Li, Junsong Liu, Chuanbin Liu, Zhiyi Fang, Feng Cao
Topics & Concepts
Unfolded protein responseTauroursodeoxycholic acidEndoplasmic reticulumVascular smooth muscleOxidative stressEndocrinologyCHOPInternal medicineCell biologyBiologyChemistryMedicineSmooth muscleSpaceflight effects on biologyEndoplasmic Reticulum Stress and DiseaseMitochondrial Function and Pathology