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Finger-Actuated Microneedle Array for Sampling Body Fluids

Misagh Rezapour Sarabi, Abdollah Ahmadpour, Ali K. Yetisen, Savaş Taşoğlu

2021Applied Sciences32 citationsDOIOpen Access PDF

Abstract

The application of microneedles (MNs) for minimally invasive biological fluid sampling is rapidly emerging, offering a user-friendly approach with decreased insertion pain and less harm to the tissues compared to conventional needles. Here, a finger-powered microneedle array (MNA) integrated with a microfluidic chip was conceptualized to extract body fluid samples. Actuated by finger pressure, the microfluidic device enables an efficient approach for the user to collect their own body fluids in a simple and fast manner without the requirement for a healthcare worker. The processes for extracting human blood and interstitial fluid (ISF) from the body and the flow across the device, estimating the amount of the extracted fluid, were simulated. The design in this work can be utilized for the minimally invasive personalized medical equipment offering a simple usage procedure.

Topics & Concepts

MicrofluidicsBiomedical engineeringComputer scienceInterstitial fluidMaterials scienceBody fluidNanotechnologyEngineeringMedicinePathologyInternal medicineAdvancements in Transdermal Drug DeliveryMicrofluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing Technologies
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