BmKK2, a thermostable Kv1.3 blocker from Buthus martensii Karsch (BmK) scorpion, inhibits the activation of macrophages via Kv1.3-NF-κB- NLRP3 axis
Zhiheng Wang, Ming Sang, Yuxin Zhang, Shengjun Chen, Song Li, Yonggen Chen, Erjin Xu, Qian Zhou, W. Xu, Chenglei Zhao, Dawei Wang, Wuguang Lu, Peng Cao
Topics & Concepts
VenomIn vivoScorpion VenomsInflammationAnti-inflammatoryPharmacologyScorpionMacrophageChemistryMolecular biologyIn vitroMedicineBiologyBiochemistryImmunologyBiotechnologyInflammasome and immune disordersIon channel regulation and functionIon Channels and Receptors