Identification of potential therapeutic targets for Alzheimer's disease from the proteomes of plasma and cerebrospinal fluid in a multicenter Mendelian randomization study
Shengnan Wang, Jianxin Xi, Mengyuan Zhang, Jianglong Wang
Topics & Concepts
Mendelian randomizationCerebrospinal fluidDiseaseDementiaMedicineFrontotemporal lobar degenerationAlzheimer's diseaseAlzheimer's Disease Neuroimaging InitiativeBioinformaticsInternal medicineGenome-wide association studyOncologyBiologyGeneticsGeneFrontotemporal dementiaGenotypeSingle-nucleotide polymorphismGenetic variantsAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsPhosphodiesterase function and regulation