10-Year Trends of Antithrombotic Therapy Status and Outcomes in Japanese Atrial Fibrillation Patients ― The Fushimi AF Registry ―
Masaharu Akao, Hisashi Ogawa, Nobutoyo Masunaga, Kimihito Minami, Kenjiro Ishigami, Syuhei Ikeda, Kosuke Doi, Yasuhiro Hamatani, Takashi Yoshizawa, Yuya Ide, Akiko Fujino, Mitsuru Ishii, Moritake Iguchi, Hiromichi Wada, Koji Hasegawa, Hikari Tsuji, Masahiro Esato, Mitsuru Abe, for the Fushimi AF Registry Investigators
Abstract
BACKGROUND: Atrial fibrillation (AF) increases the risk of stroke and death. Oral anticoagulants (OAC) are highly effective in reducing the risk of stroke, and direct oral anticoagulants (DOAC) became available worldwide in 2011. METHODS AND RESULTS: score 2.03 vs. 2.04, and HAS-BLED score 1.67 vs. 1.77, respectively). CONCLUSIONS: Over the past 10 years, there has been a major transition in antithrombotic therapy and a decline in the incidence of adverse events in AF patients.