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Genuine carbene versus carbene‐like reactivity

Jan Lorkowski, Patrick Yorkgitis, Melinda R. Serrato, Milan Gembický, Cezary Pietraszuk, Guy Bertrand, Rodolphe Jazzar

2024Angewandte Chemie International Edition17 citationsDOIOpen Access PDF

Abstract

Singlet carbenes are not always isolable and often even elude direct detection. When they escape observation, their formation can sometimes be evidenced by in situ trapping experiments. However, is carbene-like reactivity genuine evidence of carbene formation? Herein, using the first example of a spectroscopically characterized cyclic (amino)(aryl)carbene (CAArC), we cast doubt on the most common carbene trapping reactions as sufficient proof of carbene formation.

Topics & Concepts

CarbeneReactivity (psychology)ChemistryTransition metal carbene complexSinglet stateArylPhotochemistryOrganic chemistryCatalysisPhysicsExcited stateMedicinePathologyNuclear physicsAlternative medicineAlkylChemical Reactions and MechanismsCyclopropane Reaction MechanismsCatalytic Cross-Coupling Reactions
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