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Bidirectional relationship between gastrointestinal cancer and depression: The key is in the microbiota-gut-brain axis

Bryan Adrián Priego-Parra, J.M. Remes-Troche

2024World Journal of Gastroenterology14 citationsDOIOpen Access PDF

Abstract

, which explores the complex relationship between depression and gastric cancer and offers perspectives. Key topics discussed include the microbiota-gut-brain axis, dysbiosis, and the influence of microbial metabolites in homeostasis. Additionally, we address toxic stress caused by hypothalamic-pituitary-adrenal axis dysregulation, psychological assessments, and future research directions. Our Editorial aims to expand the understanding of the bidirectional relationship between depression and gastrointestinal cancer.

Topics & Concepts

Gut–brain axisDysbiosisGut floraDepression (economics)CancerMedicineBrain cancerBioinformaticsNeuroscienceInternal medicinePsychologyBiologyImmunologyEconomicsMacroeconomicsGut microbiota and healthDiet and metabolism studiesTryptophan and brain disorders
Bidirectional relationship between gastrointestinal cancer and depression: The key is in the microbiota-gut-brain axis | Litcius