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Synthesis of Subporphyrin Free Bases

Le Liu, Jinseok Kim, Ling Xu, Yutao Rao, Mingbo Zhou, Bangshao Yin, Juwon Oh, Dongho Kim, Atsuhiro Osuka, Jianxin Song

2022Angewandte Chemie International Edition24 citationsDOI

Abstract

Abstract B III subporphyrins are the legitimate ring‐contracted porphyrins consisting of three pyrroles and three meso ‐carbons and their chemistry has been extensively developed since the first synthesis in 2006. However, subporphyrin free bases have never been synthesized, despite tremendous attempts to remove the B III ion. Here we report that Suzuki–Miyaura coupling between α,α′‐diborylated tripyrrane 1 and tetrabromide 5 gave subporphyrin free bases 6 , 6 A , and free base dimer 7 in 6 %, 4 %, and 2 % yields as the first examples. Subporphyrin free bases exhibit curved bowl‐like structures and distinct 14π‐aromaticity. Steady‐state and time‐resolved spectroscopy revealed that the excited‐state behaviors of the subporphyrin free bases are comparable with those of the corresponding B III subporphyrins. Rotational relaxation processes in the excited states have been revealed, which enhance the electronic interactions with the meso ‐aryl substituents and between the two subporphyrins.

Topics & Concepts

ChemistryExcited stateAromaticityFree baseDimerArylRelaxation (psychology)Free stateRing (chemistry)Computational chemistrySpectroscopyChemical physicsPhotochemistryStereochemistryCrystallographyMoleculeOrganic chemistryAtomic physicsSalt (chemistry)PsychologyAlkylPhysicsSocial psychologyQuantum mechanicsAncient historyHistoryPorphyrin and Phthalocyanine ChemistrySynthesis and Properties of Aromatic CompoundsLuminescence and Fluorescent Materials
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