Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction
Wenjuan Zhou, Chenhao Xu, Guanjun Dong, Hui Qiao, Jing Yang, Hong‐Min Liu, Lina Ding, Kai Sun, Wen Zhao
Topics & Concepts
NeddylationChemistryCullinIC50Ubiquitin ligaseUbiquitinThiolIn vitroProtein–protein interactionBiochemistryGeneUbiquitin and proteasome pathwaysAutophagy in Disease and TherapyCancer-related Molecular Pathways