Litcius/Paper detail

Amgen overcomes historically undruggable target, with FDA nod for first KRAS inhibitor

Asher Mullard

2021Nature Reviews Drug Discovery17 citationsDOI

Topics & Concepts

NodKRASPharmacologyMedicineComputational biologyCancer researchCancerBiologyDiabetes mellitusInternal medicineColorectal cancerEndocrinologyProtein Kinase Regulation and GTPase SignalingNeutrophil, Myeloperoxidase and Oxidative MechanismsCancer, Hypoxia, and Metabolism