Lycopene protects against central and peripheral neuropathy by inhibiting oxaliplatin-induced ATF-6 pathway, apoptosis, inflammation and oxidative stress in brains and sciatic tissues of rats
Hamit Çelik, Sefa Küçükler, Selçuk Özdemir, Selim Çomaklı, Cihan Gür, Fatih Mehmet Kandemır, Ahmet Yardım
Topics & Concepts
Oxidative stressGlutathione peroxidaseEndocrinologyATF6Internal medicineSuperoxide dismutaseGlutathioneSciatic nerveLipid peroxidationMedicineChemistryPharmacologyApoptosisUnfolded protein responseBiochemistryEnzymeCancer Treatment and PharmacologyChemotherapy-induced organ toxicity mitigationMicrotubule and mitosis dynamics