Polymeric nanoparticles – a review
Sindhu Gillella, M Divyanjali, S Rishitha, Amzad SK, UshaKiran Reddy T, Chundayil Madathil Girish, Apparao CH
Abstract
Polymeric nanoparticles have emerged as versatile and promising platforms in the field of nanotechnology, offering unique properties and functionalities for various applications. These nanoparticles, typically ranging from 1 to 1000 nanometers in size, are composed of biocompatible or biodegradable polymers, offering controlled drug delivery, imaging capabilities, and targeted therapy. This abstract provides an overview of the synthesis methods, characterization techniques, and applications of polymeric nanoparticles in drug delivery, gene therapy, diagnostics, and imaging. Various polymeric materials, including synthetic and natural polymers, are explored for their suitability in nanoparticle formulations. The choice of polymers influences crucial properties such as biocompatibility, biodegradability, and controlled drug release kinetics, enhancing the therapeutic efficacy and reducing side effects. The ability to encapsulate a diverse range of payloads, including hydrophobic and hydrophilic compounds, makes polymeric nanoparticles highly adaptable for different applications.