Aminoglycosides Antagonize Bacteriophage Proliferation, Attenuating Phage Suppression of Bacterial Growth, Biofilm Formation, and Antibiotic Resistance
Pengxiao Zuo, Pingfeng Yu, Pedro J. J. Alvarez
Abstract
The coexistence of residual antibiotics and phages is common in many environments, which underscores the need to understand their interactive effects on bacteria and the implications for antibiotic resistance propagation. Here, aminoglycosides acting as bacterial protein synthesis inhibitors impeded the replication of various phages.
Topics & Concepts
MicrobiologyTetracyclineKanamycinBacteriophageAntibioticsBiofilmBiologyAntibiotic resistanceEscherichia coliBacteriaGeneGeneticsBacteriophages and microbial interactionsMicrobial infections and disease researchGenomics and Phylogenetic Studies