Litcius/Paper detail

Tubulin acetyltransferases access and modify the microtubule luminal K40 residue through anchors in taxane-binding pockets

Jingyi Luo, Wai Hei Lam, Daqi Yu, Victor C. Chao, Marc Nicholas Zopfi, Chen Jing Khoo, Chang Zhao, Shan Yan, Zheng Liu, Xiang Li, Chaogu Zheng, Yuanliang Zhai, Shih-Chieh Ti

2024Nature Structural & Molecular Biology16 citationsDOI

Topics & Concepts

AcetyltransferasesTaxaneMicrotubuleChemistryResidue (chemistry)BiochemistryCell biologyPlasma protein bindingTubulinHistone AcetyltransferasesBinding siteBiologyAcetylationCancerGeneGeneticsBreast cancerMicrotubule and mitosis dynamicsUbiquitin and proteasome pathwaysCancer-related Molecular Pathways