Smart biomaterials for enhancing cancer therapy by overcoming tumor hypoxia: a review
Samar A. Salim, Taher A. Salaheldin, Mohamed M. Elmazar, A. F. Abdel-Aziz, Elbadawy A. Kamoun
Abstract
in tumors, and using polymeric systems as oxygen carriers. Herein, this review provides an overview of the relationship between hypoxia in tumor cells and its role in the limitation of different cancer therapies alongside the numerous strategies for oxygen delivery using polysaccharides and other biomaterials as carriers and for oxygen generation.
Topics & Concepts
Hypoxia (environmental)Tumor hypoxiaRadiation therapyCancer cellPhotothermal therapyCancer therapyGelatinCancerMedicineOxygenCancer researchBiomedical engineeringMaterials scienceNanotechnologyChemistryInternal medicineBiochemistryOrganic chemistryNanoplatforms for cancer theranosticsSupramolecular Self-Assembly in MaterialsRNA Interference and Gene Delivery