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Discovery of endogenous nitroxyl as a new redox player in Arabidopsis thaliana

Magdalena Arasimowicz‐Jelonek, Jolanta Floryszak‐Wieczorek, S. Suárez, Fabio Doctorovich, Ewa Sobieszczuk‐Nowicka, S. Bruce King, Grzegorz Milczarek, Tomasz Rębiś, Joanna Gajewska, Przemysław Jagodzik, Marek Żywicki

2022Nature Plants31 citationsDOIOpen Access PDF

Abstract

Nitroxyl (HNO) is the one-electron reduced and protonated congener of nitric oxide (•NO), owning a distinct chemical profile. Based on real-time detection, we demonstrate that HNO is endogenously formed in Arabidopsis. Senescence and hypoxia induce shifts in the redox balance, triggering HNO decay or formation mediated by non-enzymatic •NO/HNO interconversion with cellular reductants. The stimuli-dependent HNO generation supports or competes with •NO signalling, depending on the local redox environment.

Topics & Concepts

RedoxNitroxylNitric oxideChemistryArabidopsisArabidopsis thalianaEndogenyProtonationBiophysicsBiochemistryPhotochemistryBiologyInorganic chemistryOrganic chemistryMutantIonGenePlant responses to water stressPlant Stress Responses and TolerancePhotosynthetic Processes and Mechanisms
Discovery of endogenous nitroxyl as a new redox player in Arabidopsis thaliana | Litcius