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Pinning down the accuracy of physics-informed neural networks under laminar and turbulent-like aortic blood flow conditions

A. Aghaee, Muhammad Owais Khan

2024Computers in Biology and Medicine15 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Physics-informed neural networks (PINNs) are increasingly being used to model cardiovascular blood flow. The accuracy of PINNs is dependent on flow complexity and could deteriorate in the presence of highly-dynamical blood flow conditions, but the extent of this relationship is currently unknown. Therefore, we investigated the accuracy and performance of PINNs under a range of blood flow conditions, from laminar to turbulent-like flows. METHODS: ) cases were trained in this study. The PINNs architecture and data have been made open-sourced. RESULTS: PINNs errors increased substantially for stenosis severity >50% (stenotic Reynolds numer > 2000) due to the presence of complex turbulent-like flow features. When using 400 sensor points, PINNs velocity magnitude errors ranged from 30% for no-stenosis model to 57% for the model with 70% stenosis, and dropped to 10% and 20%, respectively when the number of sensor points were increased to 1600. PINNs velocity magnitude errors increased monotonically with turbulent intensity, particularly beyond stenosis severity of 50%. CONCLUSIONS: Our findings indicate that the accuracy of PINNs is dependent on the complexity of blood flow conditions. Using conventional PINNs architecture, the errors in trained velocity can increase substantially in the presence of turbulent-like blood flows that are typically found in various vascular pathologies.

Topics & Concepts

Laminar flowTurbulenceArtificial neural networkFlow (mathematics)Blood flowCardiologyStatistical physicsComputer sciencePhysicsMechanicsMedicineArtificial intelligenceModel Reduction and Neural NetworksNeural Networks and Reservoir ComputingCongenital heart defects research
Pinning down the accuracy of physics-informed neural networks under laminar and turbulent-like aortic blood flow conditions | Litcius