Field-Reassortment of Bluetongue Virus Illustrates Plasticity of Virus Associated Phenotypic Traits in the Arthropod Vector and Mammalian Host <i>In Vivo</i>
C. J. Sanders, Eva Veronesi, Paulina Rajko‐Nenow, Peter Mertens, Carrie Batten, Simon Gubbins, Simon Carpenter, Karin E. Darpel
Abstract
Reassortment between virus strains can lead to major shifts in the transmission parameters and virulence of segmented RNA viruses, with consequences for spread, persistence, and impact. The ability of these pathogens to adapt rapidly to their environment through this mechanism presents a major challenge in defining the conditions under which emergence can occur.
Topics & Concepts
ReassortmentBiologyVirologyCulicoidesArbovirusVirusGeneticsGenomeHost (biology)Viral replicationZoologyGeneDiseaseCoronavirus disease 2019 (COVID-19)MedicineInfectious disease (medical specialty)PathologyVector-Borne Animal DiseasesAnimal Disease Management and EpidemiologyViral Infections and Vectors