Heteroconjugates of quercetin with 4′-<i>O</i>-sulfate selectively accumulate in rat plasma due to limited urinary excretion
Seiya Tanaka, Aphichat Trakooncharoenvit, Miyu Nishikawa, Shinichi Ikushiro, Hiroshi Hara
Abstract
Seven positional isomers of quercetin heteroconjugates were identified and quantified in rat plasma and urine. Heteroconjugates with 4′-sulfate were hardly excreted into urine and accumulate in plasma.
Topics & Concepts
QuercetinGlucuronideUrineChemistryExcretionSulfateChromatographyBiochemistryAntioxidantOrganic chemistryCholesterol and Lipid MetabolismPhytochemicals and Antioxidant ActivitiesProtein Kinase Regulation and GTPase Signaling