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The anticancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery

Liang Liu, Angela M Yu, Xiuye Wang, Lindsey V. Soles, Xueyi Teng, Yi-Ling Chen, Yoseop Yoon, Kristianna S.K. Sarkan, Marielle Cárdenas Valdez, Johannes Linder, Whitney England, Robert C. Spitale, Zhaoxia Yu, Ivan Marazzi, Feng Qiao, Wei Li, Georg Seelig, Yongsheng Shi

2023Nature Structural & Molecular Biology15 citationsDOIOpen Access PDF

Topics & Concepts

Messenger RNACleavage (geology)RNABiologyIn vitroTranscription (linguistics)Sequence (biology)Computational biologyChemistryMolecular biologyGeneticsGenePaleontologyPhilosophyFracture (geology)LinguisticsRNA and protein synthesis mechanismsRNA Research and SplicingRNA modifications and cancer
The anticancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3′ processing machinery | Litcius