Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GeparNuevo
Thomas Karn, Carsten Denkert, Karsten E. Weber, Uwe Holtrich, Claus Hanusch, Bruno V. Sinn, Brandon W. Higgs, Paul Jank, Hans‐Peter Sinn, Jens Huober, Christoph Becker, Jens‐Uwe Blohmer, Frederik Marmé, Wolfgang Schmitt, Song Wu, Marion van Mackelenbergh, Volkmar Müller, Christian Schem, Elmar Stickeler, Peter A. Fasching, Christian Jackisch, Michael Untch, Andreas Schneeweiß, Sibylle Loibl
Topics & Concepts
MedicineImmune systemNeoadjuvant therapyComplete responseImmune checkpointOncologyCancer researchInternal medicineImmunologyImmunotherapyChemotherapyCancerBreast cancerCancer Immunotherapy and BiomarkersBreast Cancer Treatment StudiesPARP inhibition in cancer therapy