Adeno-associated virus (AAV) 9-mediated gene delivery of Nurr1 and Foxa2 ameliorates symptoms and pathologies of Alzheimer disease model mice by suppressing neuro-inflammation and glial pathology
Yunseon Yang, Min‐Jong Seok, Ye Eun Kim, Yunjung Choi, Jae‐Jin Song, Yanuar Alan Sulistio, Seonghoon Kim, Mi‐Yoon Chang, Soo‐Jin Oh, Min‐Ho Nam, Yun Kyung Kim, Tae‐Gyun Kim, Heh‐In Im, Seong‐Ho Koh, Sang‐Hun Lee
Topics & Concepts
Adeno-associated virusGenetic enhancementGene deliveryInflammationFOXA2BiologyViral vectorNeuroscienceMedicinePathologyImmunologyVector (molecular biology)Gene expressionGeneGeneticsRecombinant DNANuclear Receptors and SignalingRNA Interference and Gene DeliveryRNA regulation and disease